A flavonoid; reduces autophagy

Quercetin (hydrate) – 50 g

Brand:
Cayman
CAS:
849061-97-8
Storage:
22
UN-No:
Limited Quantity - 2811 / 6.1

Quercetin is an abundant flavonoid that has been isolated from a variety of fruits and vegetables and has diverse biological activities, including antioxidant, anticancer, and anti-inflammatory properties.{36990,36991,36992} Quercetin (5-100 mg/kg) reduces autophagy, decreases the levels of reactive oxygen species (ROS) and malondialdehyde (MDA) content, and increases total antioxidant capacity in the kidney in a mouse model of cadmium-induced autophagy.{36991} It reduces tumor growth, induces apoptosis, and halts the cell cycle at the G1 phase in an HL60 mouse xenograft model when administered at a dose of 120 mg/kg every four days.{36990} Quercetin (30 µM) also inhibits histamine release from antigen-stimulated RBL-2H3 cells and decreases the expression of TNF-α, IL-1β, IL-6, and IL-8 induced by PMACI in HMC-1 cells.{36992}  

 

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SKU: 10005169 - 50 g Category:

Description

A flavonoid; reduces autophagy, decreases the levels of ROS and MDA content, and increases total antioxidant capacity in the kidney in a mouse model of cadmium-induced autophagy at 5-100 mg/kg; reduces tumor growth in an HL60 mouse xenograft model at 120 mg/kg every four days; inhibits histamine release from antigen-stimulated RBL-2H3 cells and decreases the expression of pro-inflammatory cytokines in HMC-1 cells

Formal name: 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one, hydrate

Synonyms: 

Molecular weight: 302.2

CAS: 849061-97-8

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Natural Products|Flavonoids||Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Research Area|Cancer|Cell Cycle|G1||Research Area|Cancer|Cell Death|Apoptosis||Research Area|Immunology & Inflammation|Allergy||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity||Research Area|Oxidative Stress & Reactive Species|Lipid Peroxidation||Research Area|Oxidative Stress & Reactive Species|Reactive Oxygen

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