A minor CYP450 metabolite of arachidonic acid that stimulates vasodilation of rabbit kidney

16(R)-HETE – 50 µg

Brand:
Cayman
CAS:
183509-22-0
Storage:
-20
UN-No:
De Minimis - 1170 / 3

Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. 16-HETE is a minor CYP450 metabolite of arachidonic acid released by the kidney upon angiotensin II stimulation that demonstrates stereospecific biological activity. Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. 16-HETE is a minor CYP450 metabolite of arachidonic acid released by the kidney upon angiotensin II stimulation that demonstrates stereospecific biological activity. 16(S)-HETE inhibits proximal tubule ATPase activity by as much as 60% at a concentration of 2 µM.{3825}  

 

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SKU: 10004385 - 50 µg Category:

Description

A minor CYP450 metabolite of arachidonic acid that stimulates vasodilation of rabbit kidney

Formal name: 16R-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid

Synonyms: 

Molecular weight: 320.5

CAS: 183509-22-0

Purity: ≥98%

Formulation: A solution in ethanol

Product Type|Biochemicals|Lipids|Hydroxy/Hydroperoxy/ Epoxy/Oxo Eicosanoids||Product Type|Biochemicals|Small Molecule Inhibitors|ATPases||Research Area|Cardiovascular System|Kidney & Renal Disease||Research Area|Lipid Biochemistry|Reactive O2/N2 Pathways

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