Double bond isomer of trans-resveratrol

cis-Resveratrol – 50 mg

Brand:
Cayman
CAS:
61434-67-1
Storage:
-80
UN-No:
De Minimis - 1170 / 3

Resveratrol is a potent phenolic antioxidant found in grapes, red wine, and various berries that also has antiproliferative and anti-inflammatory activity.{9146} cis-Resveratrol is the double bond isomer of trans-resveratrol, the more often studied and naturally abundant of the two resveratrol isomers. cis-Resveratrol exhibits antioxidant activity in the µM range similar to that observed with trans-resveratrol.{15185} It blocks production of reactive oxygen species (ROS) by inhibition of NAD(P)H oxidase and also inhibits production of nitric oxide.{15185} At a concentration of 100 µM, cis-resveratrol significantly inhibits the expression of genes related to the Rel/NF-κB/IκB family, adhesion molecules, and acute-phase proteins in LPS and INF-γ-stimulated murine peritoneal macrophages.{15184} cis-Resveratrol inhibits uptake of noradrenaline and 5-HT by synaptosomes from rat brain with IC50 values of 79 and 51 µM, respectively.{15183} It also inhibits human monoamine oxidase-A (MOA-A) and MOA-B with IC50 values of 25 and 61 µM, respectively, which is similar to, but slightly less effective than, values obtained with trans-resveratrol.{15183}  

 

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SKU: 10004235 - 50 mg Category:

Description

Double bond isomer of trans-resveratrol, the more often studied and naturally abundant of the two resveratrol isomers; exhibits antioxidant activity in the micromolar range similar to that observed with trans-resveratrol

Formal name: 5[(1Z)-2-(4-hydroxyphenyl)ethenyl]-1,3-benzenediol

Synonyms:  (Z)-Resveratrol

Molecular weight: 228.2

CAS: 61434-67-1

Purity: ≥98% (may contain 1-5% trans)

Formulation: A solution in ethanol

Product Type|Biochemicals|Natural Products||Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Product Type|Biochemicals|Small Molecule Inhibitors||Research Area|Immunology & Inflammation|Innate Immunity|Pattern Recognition||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity||Research Area|Oxidative Stress & Reactive Species|Reactive Oxygen

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