Description
Cytosolic PGE synthase (cPGES) is a glutathione-dependent enzyme with a predicted size of 18.6 kDa (23 kDa on SDS-PAGE). The enzyme is expressed in a wide variety of tissues and cells, the levels of which are unaffected by treatment with IL-1β and TNFα.{8691} However, enzyme expression increases approximately 3-fold in rat brain following LPS treatment.{8691} Microsomal PGE synthase (mPGES) is a 16 kDa protein expressed in a variety of tissues.{7229} In contrast to cPGES, mPGES protein expression is increases in A549 cells following treatment with IL-1β.{7229} The two enzymes show <10% homology at the amino acid level.
Synonyms: cPGE Synthase|cPGES|Hsp90 Co-chaperone|p23|Teolomerate-binding protein p23
Immunogen: Full-length, human recombinant cytosolic prostaglandin E synthase
Formulation: Affinity-purified polyclonal antibody
Isotype:
Applications: WB, ICC
Origin: Animal/Rabbit
Stability: 365 days
Application|Immunocytochemistry||Application|Western Blot||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway